An Evaluation of the Switch from Standard Factor VIII Prophylaxis to Prophylaxis with an Extended Half-Life, Pegylated, Full-length Recombinant Factor VIII (BAX 855)

An Evaluation of the Switch from Standard Factor VIII Prophylaxis to Prophylaxis with an Extended Half-Life, Pegylated, Full-length Recombinant Factor VIII (BAX 855)

AWARDED/PRESENTED: 2015
GRANT/PROGRAM:
Bleeding Disorders Conference
Clinical Research/Clinical Trials
RESEARCHERS:
Oleksandra Stasyshyn, Ralph Gruppo, Barbara Konkle, Tung Wynn, Marilyn Manco-Johnson, Pratima Chowdary, Vladimir Komrska, Laimonas Griskevicius, Elaine Eyster, Krzysztof Chojnowski, Werner Engl, Lisa Patrone, Brigitt Abbuehl
The Effects of Hemophilia on Socialization

The Effects of Hemophilia on Socialization

AWARDED/PRESENTED: 2015
GRANT/PROGRAM:
Bleeding Disorders Conference
Psychosocial Issues
RESEARCHERS:
Aric Parnes, Christine Mitchell, Rachel Wentz, Federico Campigotto, Latoya Lashley, Cathee Brunswick, Donna Neuberg, Judith Lin
In vivo Imaging of Bleeds in Hemophilia B

In vivo Imaging of Bleeds in Hemophilia B

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia B (Factor IX/F9)
Hemophilic Arthropathy
Pain
Author(s):
Elizabeth Chappell

Dr. Chappell's research project will develop a model for characterizing bleeding in hemophilia and particularly in joints. Using mouse models of hematoma formation and knee joint bleeding, Dr. Chappell will use 3D fluorescent imaging technology in "living" hemophilia B mice to better trace bleeding over time- from induction of a bleed to its resolution. This project will provide additional insights on the basic science underlying hemophilic bleeds, not to mention the optimal interventions and timing of treatment to potentially prevent damage caused by bleeds. Dr. Chappell earned her Ph.D. in Pharmaceutical Sciences from UNC Chapel Hill in 2013. She will pursue her research under the mentorship of Dr. Dougald Monroe, Professor in the Division of Hematology/Oncology, UNC School of Medicine and the UNC McAllister Heart Institute.

Leading an Active Lifestyle with Hemophilia B: Estimating the Bleeding Risk with Different FIX Treatment Regimens

Leading an Active Lifestyle with Hemophilia B: Estimating the Bleeding Risk with Different FIX Treatment Regimens

Year: 2015
Grants:
Bleeding Disorders Conference
Biomedical/Coagulation Research
Author(s):
Yan Xiong, Alexandra Khachatryan, Josh Epstein