Factor II (Prothrombin) Deficiency
Factor II (FII) deficiency, also called prothrombin deficiency, was first identified in 1947 by Dr. Armand Quick. The incidence is estimated at 1 in 2 million in the general population. Factor II…
Factor V (Labile Factor, Proaccelerin) Deficiency (Owren’s Disease, Parahemophilia)Factor V (FV) deficiency was first described in a Norwegian patient in 1943 and reported by Dr. Paul Owren in 1947. Its incidence is about 1 in 1 million; fewer…
Factor VII (Labile Factor or Proconvertin) Deficiency (Alexander’s Disease)
Factor VII (FVII), or proconvertin, deficiency was first recognized in 1951. Considered the most common of rare bleeding disorders its incidence is estimated at 1…
FACTOR X (Stuart-Prower Factor) DEFICIENCY
Factor X (FX), or Stuart-Prower factor, deficiency was first identified in the 1950s in the US and England in two patients: Rufus Stuart and Audrey Prower. The incidence of FX deficiency is estimated at…
FACTOR XI DEFICIENCY (Hemophilia C, Plasma Thromboplastin Antecedent (PTA) Deficiency, Rosenthal Syndrome)Factor XI (FXI) deficiency, also called hemophilia C, plasma thromboplastin antecedent deficiency and Rosenthal syndrome, was first recognized…
FACTOR XII (Hageman Factor) DEFICIENCY
Factor XII (FXII) deficiency, also called Hageman factor deficiency, was first identified in 1955 in John Hageman. Its incidence is estimated at 1 in a million. FXII deficiency is inherited in an autosomal…
FACTOR XIII (Fibrin Stabilizing Factor) DEFICIENCY
Factor XIII (FXIII), or fibrin stabilizing factor, deficiency was first reported in the literature in 1960. It is the rarest factor deficiency, occurring in 1 per 5 million births…
Treatment Options for Bleeding DisordersThere are many different types of therapies to treat bleeding disorders, and new ones are in development. Each person may respond to a treatment in their own way, so it is important to work closely with your…
Innovative Therapies for Bleeding DisordersOver the last few years, new, innovative therapies have been approved to treat bleeding disorders. These treatments are sometimes referred to as “novel” therapies, because they work differently in the body…
Gene Therapy Glossary of TermsA | B | C | D | E | F | G | H | I…