En EspañolIf you are infusing clotting factor replacement products, you can develop an inhibitor. Health care providers are not completely sure why this happens, but they know certain people are more likely to develop an inhibitor than others.
En Español If you have hemophilia (A or B) or von Willebrand disease (VWD) and use clotting factor replacement products, then talk to your health care provider about the chances of developing an inhibitor and about getting tested. Ask…
En EspañolFinancial ConsiderationsThe cost of treating an inhibitor can be very high. Bleeding Disorders treatment is already expensive, and treating an inhibitor can be even more costly. It’s important to acknowledge that new treatments are…
En EspañolFor many years, experts have been talking about the importance of studying hemophilia inhibitors. Thanks to technology that helps understand genes and mutations, health care providers and scientists now know more about the risks of…
What Is Hemophilia A?Hemophilia A, also called factor VIII (8) deficiency or classic hemophilia, is a genetic disorder caused by missing or defective factor VIII (FVIII), a clotting protein. Although it is passed down from parents to children, about…
What is Hemophilia BHemophilia B, also called factor IX (FIX) deficiency or Christmas disease, is a genetic disorder caused by missing or defective factor IX, a clotting protein. Although it is passed down from parents to children, about 1/3 of…
What is von Willebrand Disease?Von Willebrand disease (VWD) is an inheritable bleeding disorder. Many different proteins are needed to make a person’s blood clot successfully. People with VWD are either missing or low in the clotting protein von…
What Are Rare Bleeding Disorders?In the US, a rare disease or disorder is defined as one that affects fewer than 200,000 people. This means hemophilia A and B, and the less-common factor deficiencies such as I, II, V, VII, X, XI, XII and XIII, are…
What are Platelet Disorders?Platelets play an important role in blood clotting, so when a person has a low number of platelets, too many platelets or their platelets don’t work the way they should, they have a platelet disorder. People with platelet…
Factor I (Fibrinogen) Deficiency
Factor I deficiency is a collective term for three rare inherited fibrinogen deficiencies. It was first described in 1920 by two German physicians. Fibrinogen helps platelets stick together to form the initial “…