Objectives:
The primary aims of this study are to 1) evaluate the prevalence of depression and anxiety among adult persons with hemophilia (PWH) and 2) explore relationships between depression, anxiety, chronic pain, and…
Bleeding disorders are a group of conditions that result when the blood cannot clot properly (American Society of Hematology, 2017). The most frequently occurring bleeding disorders include von Willebrand Disease (VWD), Hemophilia A, and Hemophilia…
Background:
The impact of family history on mothers of sons with hemophilia is unknown. The primary purpose of this study was to determine whether differences exist in perceived vulnerability of sons, protective behaviors toward…
Background:
A high-purity plasma-derived FX concentrate (pdFX) has been developed for treatment of hereditary FX deficiency, an autosomal recessive disorder.
Aim:
This post hoc analysis describes the…
Background:
Congenital FXD is a rare bleeding disorder characterized by spontaneous joint and mucocutaneous bleeding and gastrointestinal or intracranial hemorrhage. pdFX is a US- and EU-approved treatment for congenital FXD, but…
Objective:
Patients with hereditary bleeding disorders have been included in Phase 2 and 3 clinical trials of sofosbuvir (SOF), ledipasvir/sofosbuvir (LDV/SOF), sofosbuvir/velpatasvir (SOF/VEL), and sofosbuvir/velpatasvir/…
Background/Objective:
Hemophilia is a bleeding disorder caused by the body’s inability to accomplish the natural clotting process. People with hemophilia experience bleeds because there is an inadequate amount of thrombin due to…