Target Joint Spontaneous annualized bleed rate (sABR) Reduction: results from a pivotal trial of once weekly BeneFIX (nonacog alfa) in Hemophilia B subjects
SPACE (Study of Prophylaxis ACtivity, and Effectiveness): An interim descriptive analysis of patient activity levels and participation
Objective: Personalizing treatment to a patient’s lifestyle and promoting overall health and wellness in persons with hemophilia (PWH) is essential to optimizing outcomes. There is limited evidence that correlates how activity…
Increased physical activity levels and improvement in treatment outcomes in patients who switch from on-demand to prophylaxis with BAX 855
An Evaluation of the Switch from Standard Factor VIII Prophylaxis to Prophylaxis with an Extended Half-Life, Pegylated, Full-length Recombinant Factor VIII (BAX 855)
Objective: This report assesses the changes in bleeding patterns as previously treated severe hemophilia A patients were switched from their pre-study standard factor VIII (FVIII) prophylactic treatment regimen to prophylaxis…
Update on a phase 1/2 open-label trial of BAX 335, an adeno-associated virus 8 (AAV8) vector-based gene therapy program for hemophilia B
HEMO-milestones tool increases assessment of self-management competency and plan for skill building in patients with hemophilia
Attainment of self-management skills, disease knowledge, and a documented transition plan are key elements for smooth transfer from pediatric to adult care for patients with chronic disease. Our hemophilia center had no standardized approach for…
Effect of hemophilia treatment center monitoring on bleeding rates
Objective: To assess the effect of digital monitoring on bleeding rates in patients with hemophilia A using prophylaxis. Methods: A total of 294 eligible patients with hemophilia A were included in our…
Assessment of motor proficiency in people with bleeding disorders using the Bruininks-Oseretsky Test of Motor Proficiency, Second Edition (BOT-2™)
Background: Activity limiting joint disease has greatly decreased with the introduction of prophylactic treatment for people with severe bleeding disorders. Previous research using the Bruininks-Oseretsky Test of Motor…
Adopting and Piloting the Patient Safety and Clinical Pharmacy Services Collaborative (PSPC) breakthrough model to transform and significantly improve adherence, improve health status and bring patients under control in the Hemophilia Community
Intervention of Mexicans children and teenagers with hemophilia for their social integration
Hemophilia is a rare bleeding disorder in which the blood doesn't clot normally. (National Heart, Lung, and Blood Institute, 2013). It mostly affects males.(Raabe, 2008). For parents hearing that their new baby has hemophilia can be stressful and…