NBDF funds a broad range of research programs that seek to increase our understanding of the science behind bleeding disorders, how they affect people's lives, and pathways to better treatments and cures.

Exploiting Mouse Models to Elucidate the Cellular and Molecular Mechanisms Involved in the Pathogenesis of Platelet Storage Pool Deficiencies

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Platelets
Author(s):
Lisa S. Webb

Function of Coagulation Factor V in Plasma and Platelet Pools

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Platelets
Author(s):
Hongmin Sun

Development of a Novel Genomic Transfer Approach for the Treatment of Hemophilia Based on Transduction of Adipose Tissue Using Replication-Defective HSV-1 Vectors

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Julie Fradette

Gene Therapy for Hemophilia B by Direct Intramuscular Injections of Recombinant Adeno Associated Virus Serotype Vectors

Year:
-
Grants:
Career Development Award
Gene Therapy
Hemophilia B (Factor IX/F9)
Author(s):
Hengjun Chao
Anja_Ehrhardt

Development of Improved Adenoviral Vectors Lacking All Adenoviral Coding Sequences for Hemophilia Gene Therapy

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Anja Ehrardt

Molecular Mechanisms of Combined Factors V and VIII Deficiency

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Factor V
Hemophilia A (Factor VIII/F8)
Author(s):
Bin Zhang

Study of Interactive Sites of Factor VIIIa with Factor IXa

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Peter Vincent Jenkins
Roland Herzog

Immunology of Liver-Derived Expression of Factor IX from AAV Vectors

Year:
-
Grants:
Career Development Award
Hemophilia B (Factor IX/F9)
Gene Therapy
Author(s):
Roland W. Herzog

Correction of Hemophilia with Lentiviral Vectors

Year:
-
Grants:
Career Development Award
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Gene Therapy
Author(s):
Tal Kafri
Steven Pipe

Development and Characterization of Novel Genetically Engineered Factor VIII Molecules with Increased Activity and Stability

Year:
-
Grants:
Career Development Award
Hemophilia A (Factor VIII/F8)
Author(s):
Steven Wesley Pipe

Treatment of a Mouse Model of Hemophilia Using AAV Vectors Expressing Murine Factor VIII

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Gene Therapy
Author(s):
Cathryn Sanghae Mah

Correction of Factor VIII Deficiency by Nonprimate Lentivirus-Based Gene Therapy

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Author(s):
Yubin Kang

Retroviral Vector-Mediated Gene Therapy for Canine Hemophilia B

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia B (Factor IX/F9)
Author(s):
Lingfei Xu

Mechanisms Involved in Transduction of Human Lentivirus in Liver: A Strategy for Hemophilia Gene Therapy

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Frank Park
Mark_Reding

T Cell Epitopes on Factor VIII

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
HIV/AIDS
Author(s):
Mark Thomas Reding

Induction of Immune Tolerance to Factor IX

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia B (Factor IX/F9)
Inhibitors
Author(s):
Bing-guan Chen

Vascular Bed-Specific Regulation of the VWF Gene

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Von Willebrand Disease
Author(s):
Jo Chao Tsai

New Therapeutics for Hepatitis C

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hepatitis/Liver Disease
Author(s):
You-Kyung Hwang
Paul_Monahan

AAV Hemophilia Gene Therapy Vectors

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Paul E. Monahan

Impact of VWF on Factor VIII Gene Targeting

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Von Willebrand Disease
Hemophilia A (Factor VIII/F8)
Author(s):
Jonathan Bernard Rosenberg