Research Presented at Our Conference | National Bleeding Disorders Foundation

A Novel Anti-Tissue Factor Pathway Inhibitor Antibody, BAY 1093884, Restores Hemostasis in Induced Hemophilia A Rabbits With Reduced Thrombogenic Potential

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

Maria Koellnberger, Axel Trabandt, Derek Sim, Volker Laux

Prevalence of high BMI in school age children with hemophilia

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Quality of Life/Outcomes Research

RESEARCHERS:

Ellen White, Alice J Cohen, Melinda Inzani

Initial Observations From the Pain, Functional Impairment, and Quality of Life (P-FiQ) Study: Patient-Reported Outcome Assessments in US Adults With Hemophilia

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Quality of Life/Outcomes Research

RESEARCHERS:

Tyler Buckner, Michael Wang, Michael Recht, Kim Baumann, Michelle Witkop, Stacie Akins, Anne Neff, Sharon Funk, Grace Hernandez, Diane Nugent, Christine Kempton, Doris Quon, David Cooper

Impact of FVIII CRM-positive status on the immunogenicity of FVIII in the hemophilia A mouse model

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

Jasmine Ito, Rylee Mercer, Brittany Chao, Michael Lenardo, John Healey, Hunter Baldwin, Shannon Meeks

Efficacy and safety of pdFX, a new high-purity factor X concentrate, in patients with mild to severe hereditary factor X deficiency undergoing surgery

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

New Products

RESEARCHERS:

Miguel Escobar, Günter Auerswald, Austin Steven, Huang James N, Miranda Norton, Carolyn Millar

Increase or Maintenance of Physical Activity in Patients Treated with Recombinant Factor IX Fc Fusion Protein (rFIXFc) in the B-LONG and Kids B-LONG Studies

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research/Clinical Trials

RESEARCHERS:

Amy Shapiro, Roshni Kulkarni, Jerzy Windyga, Margaret Ragni, John Pasi, Margareth Ozelo, Elisa Tsao, Geoffrey Allen, Baisong Mei

Target Joint Spontaneous annualized bleed rate (sABR) Reduction: results from a pivotal trial of once weekly BeneFIX (nonacog alfa) in Hemophilia B subjects

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

Bartholomew Tortella, Marcus Carr, Pablo Rendo, Lynne Smith, Kaan Kavakli

Relative Health Status of Young Adults in the Hemophilia Utilization Group Studies (HUGS)

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Quality of Life/Outcomes Research

RESEARCHERS:

Randall Curtis, Brenda Riske, Judith Baker, Megan Ullman, Xiaoli Niu, Kristi Norton, Marion Koerper, Mimi Lou, Michael Nichol

An Evaluation of the Switch from Standard Factor VIII Prophylaxis to Prophylaxis with an Extended Half-Life, Pegylated, Full-length Recombinant Factor VIII (BAX 855)

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research/Clinical Trials

RESEARCHERS:

Oleksandra Stasyshyn, Ralph Gruppo, Barbara Konkle, Tung Wynn, Marilyn Manco-Johnson, Pratima Chowdary, Vladimir Komrska, Laimonas Griskevicius, Elaine Eyster, Krzysztof Chojnowski, Werner Engl, Lisa Patrone, Brigitt Abbuehl

Reduced Polyethylene Glycol–Conjugated B-Domain–Deleted Factor VIII (PEG-BDD-FVIII) Clearance: Selective PEG Steric Modulation Without Affecting Potency

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

Eric Blasko, Lilley Leong, Derek Sim, Liang Tang, Jim Wu, Katalin Kauser, Babu Subramanyam

Effect of hemophilia treatment center monitoring on bleeding rates

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Quality of Life/Outcomes Research

RESEARCHERS:

Marc Lara, Natalie Duncan, Raquel Andres, John Chapin, Catherine McGuinn

The Effects of Hemophilia on Socialization

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Psychosocial Issues

RESEARCHERS:

Aric Parnes, Christine Mitchell, Rachel Wentz, Federico Campigotto, Latoya Lashley, Cathee Brunswick, Donna Neuberg, Judith Lin

Intervention of Mexicans children and teenagers with hemophilia for their social integration

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Psychosocial Issues

RESEARCHERS:

Ana Paola Abreu Bastar, Ana Laura Abreu Bastar

Real-world dosing of factor in hemophilia A patients

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research

RESEARCHERS:

Brieana Buckley, Terrie Livingston, Tanner Odom, Sangeeta Kirshnan

Does Quality of Life improve with successful immune tolerance induction? An illustrative case report.

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Psychosocial Issues

RESEARCHERS:

Paula Ulsh, Garrett Bergman

Retrospective Database Analysis of the Prevalence of Cardiovascular Comorbidities in a US Patient Population with Hemophilia A: Confirmation of Findings

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research

RESEARCHERS:

Jennifer Pocoski, Rajesh Kamalakar, Thomas J. Humphries

Hemophilia Genotyping Results from the My Life, Our Future Project

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research

RESEARCHERS:

Diane Aschman, M.Elaine Eyster, Steven Pipe, Michael Tarantino, Amy Shapiro, Christine L. Kempton, Sarah Ruuska, Sally McAlister, Val Bias, Barbara A. Konkle

SPINART Trial 3-Year Results With Bayer’s Sucrose-Formulated Recombinant Factor VIII: Improved Joint Function and Health-Related Quality of Life in Adults Using Prophylaxis

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research

RESEARCHERS:

Walter Hong, Jennifer Pocoski, David Raunig, Sharon Funk, Marilyn J. Manco-Johnson

Dosing Routines and Bleeding Rates Before and Following Treatment with rFVIIIFc in the A-LONG Clinical Study

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research

RESEARCHERS:

Kim Schafer, Jim Munn, Neelam Thukral, Angela Tom, James Potts, Sangeeta Krishnan, Aoife Brennan, Glenn Pierce, Sally McAlister, Amy Shapiro, Patrick Fogarty, Doris V. Quon

Safety of BAX 855, a Polyethylene Glycol (PEG) Conjugated Full-Length Recombinant Factor VIII Product

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research

RESEARCHERS:

Reinhard Stidl, Barbara Dietrich, Margit Spatzenegger, Eva-Maria Muchitsch, Mary Bossard, Friedrich Scheiflinger, Peter L. Turecek