En EspañolFor many years, experts have been talking about the importance of studying hemophilia inhibitors. Thanks to technology that helps understand genes and mutations, health care providers and scientists now know more about the risks of…
What Is Hemophilia A?Hemophilia A, also called factor VIII (8) deficiency or classic hemophilia, is a genetic disorder caused by missing or defective factor VIII (FVIII), a clotting protein. Although it is passed down from parents to children, about…
What is Hemophilia BHemophilia B, also called factor IX (FIX) deficiency or Christmas disease, is a genetic disorder caused by missing or defective factor IX, a clotting protein. Although it is passed down from parents to children, about 1/3 of…
What is von Willebrand Disease?Von Willebrand disease (VWD) is an inheritable bleeding disorder. Many different proteins are needed to make a…
What Are Rare Bleeding Disorders?In the US, a rare disease or disorder is defined as one that affects fewer than 200,000 people. This means hemophilia A and B, and the less-common factor deficiencies such as I, II, V, VII, X, XI, XII and XIII, are…
What are Platelet Disorders?Platelets play an important role in blood clotting, so when a person has a low number of platelets, too many platelets or their platelets don’t work the way they should, they have a platelet disorder. People with platelet…
Factor I (Fibrinogen) DeficiencyFactor I deficiency is a collective term for three rare inherited fibrinogen deficiencies. It was first described in 1920 by two German physicians. Fibrinogen helps platelets stick together to form the initial “plug”…
Factor II (Prothrombin) DeficiencyFactor II (FII) deficiency, also called prothrombin deficiency, was first identified in 1947 by Dr. Armand Quick. The incidence is estimated at 1 in 2 million in the general population. Factor II deficiency is…
Factor V (Labile Factor, Proaccelerin) Deficiency (Owren’s Disease, Parahemophilia)Factor V (FV) deficiency was first described in a Norwegian patient in 1943 and reported by Dr. Paul Owren in 1947. Its incidence is about 1 in 1 million; fewer…
Factor VII (Labile Factor or Proconvertin) Deficiency (Alexander’s Disease)Factor VII (FVII), or proconvertin, deficiency was first recognized in 1951. Considered the most common of rare bleeding disorders its incidence is estimated at 1 per…